A prospective study of the associations between GI, GL, carbohydrate and available dietary carbohydrate constituents (starch and simple sugar) intake and the risk of pancreatic cancer. Subjects were 482,362 participants of the NIH-AARP Diet and Health Study and were followed from 1995/96 to December 2003. An FFQ was completed at baseline. After excluding the first year of follow-up, 1,151 exocrine pancreatic cancer cases were identified. There were no associations between pancreatic cancer risk and GI, GL and total or available carbohydrates. However, subjects with a high free fructose and glucose intake had a greater risk of developing pancreatic cancer (RR 1.29, 95% CI 1.04-1.59, P for trend = 0.004 and RR 1.35, 95% CI 1.10-1.67, P for trend = 0.005 respectively).
May 2009