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A High-Sugar/Low-Fiber Meal Compared with a Low-Sugar/High-Fiber Meal Leads to Higher Leptin and Physical Activity Levels in Overweight Latina Females

Spruijt-Metz D et al. 
Journal of the American Dietetic Association 2009; 109: 1058-1063

A pilot study of the acute effects of high-sugar/low fibre meals vs. low-sugar/high-fibre meals on hormones and behaviour.  Ten overweight Latina females (age 11-12 years) were studied in a cross-over design.  On two occasions, subjects randomly received either a high-sugar/low-fibre meal, or a low-sugar/high-fibre meal after fasting.  Ad libitum snacks were provided at 120 minutes.  Glucose, insulin and leptin were measured at 0, 5, 15, 30, 60, 90 and 120 minutes.  Physical activity was measured using an observational system.  Blood glucose decreased significantly more slowly in the high-sugar/low-fibre group: at 60 minutes, total glucose was significantly higher in the high-sugar group (P=0.03).  There was no significant effect of meal type on insulin levels.  There was a significant difference in leptin levels at 90 minutes (low-sugar/high-fibre vs. high-sugar/low-fibre; 46.7 vs. 49.31 ng/mL, P=0.017).  There was no difference in subsequent ad libitum food intake.  Subjects were significantly more active after the high-sugar meal in the first 30-60 minutes after the meal: after 60-90 minutes, there was a trend for activity to be lower after the high-sugar meal compared to the low-sugar meal.

August 2009

 

 

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